Dr. Bilal Qureshi

Dr.  Bilal Qureshi

Dr. Bilal Qureshi

Lecturer at the Department of Materials

ETH Zürich

ScopeM

HPM C 55.2

Otto-Stern-Weg 3

8093 Zürich

Switzerland

Additional information

Membership

Since Membership
RMS Royal Microscopy Society

Additional information

Responsibilities

  • Cryo electron microscopy (CryoEM)
  • Image processing: Single particle analysis (SPA), on-the-fly processing workstations, CryoSPARC instances with HPC team
  • Sample preparation and data acquisition for single particle and cryo electron tomography (CryoET) and 3D Electron Crystallagraphy (3D ED)
  • Enhanced support and method development for challenging scientific questions

Teaching

  • Advanced Course: Cryogenic Electron Microscopy (CryoEM) - Lead
  • Transmission Electron Microscopy 1 (TEM1) - Contribution
  • EXCITE Zurich Summer School on Biomedical Imaging - Contribution
  • CCMX - ScopeM Course: Advanced Characterization of Materials at Micro, Nano and Atomic Scale - Contribution

Career

2020 – present  CryoEM expert & Lecturer, ScopeM, ETH Zurich, Switzerland

2019 – 2020     Senior staff scientist, Strubi, University of Oxford, United Kingdom

2017 – 2019     Postdoctoral researcher, Strube, KAUST, Saudi Arabia

2014 – 2017     Research Associate, IMPB, Charité-University of Medicine Berlin, Germany

2014                Doctorate in Biophysics, Charité-University of Medicine & Humboldt University of Berlin, Germany

2008                Diplom (M.S.) in Biophysics, Humboldt University of Berlin, Germany

Key awards and qualifications

  • Excellence Award 2020, University of Oxford, United Kingdom
  • Advanced Titan Krios training (4 weeks) by Thermo Fisher Scientific at University of Oxford, United Kingdom
  • Several fellowships in Germany incl. SFB 449, SFB 740, SFB 958, IMPRS/ZIBI

Selected publications

 

Frey L*, Ghosh D*, Qureshi BM*, Rhyner D, Guerrero-Ferreira R, Pokharna A, Kwiatkowski W, Serdiuk T, Picotti P, Riek R, Greenwald J. On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation2024 eLife doi: https://doi.org/10.7554/eLife.93562.4

Huntington B, Zhao L, Bron P, Shahul Hameed UF**, Arold ST**, Qureshi BM**. Thicker Ice Improves the Integrity and Angular Distribution of CDC48A Hexamers on Cryo-EM Grids. Front Mol Biosci. 2022 Jun 17;9:890390. doi: 10.3389/fmolb.2022.890390. PMID: 35782862; PMCID: PMC9247313.

Qureshi BM*, Behrmann E*, Schöneberg J, Loerke J, Bürger J, Mielke T, Giesebrecht J, Noé F, Lamb TD, Hofmann KP, Spahn CMT, Heck M. It takes two transducins to activate the cGMP-phosphodiesterase 6 in retinal rods. Open Biol. 2018 Aug;8(8):180075. doi: 10.1098/rsob.180075. PMID: 30068566; PMCID: PMC6119865.

Qureshi BM*, Schmidt A*, Behrmann E, Bürger J, Mielke T, Spahn CMT, Heck M, Scheerer P. Mechanistic insights into the role of prenyl-binding protein PrBP/δ in membrane dissociation of phosphodiesterase 6. Nat Commun. 2018 Jan 8;9(1):90. doi: 10.1038/s41467-017-02569-y. PMID: 29311697; PMCID: PMC5758567.

Qureshi BM*, Hofmann NE*, Arroyo-Olarte RD, Nickl B, Hoehne W, Jungblut PR, Lucius R, Scheerer P, Gupta N. Dynein light chain 8a of Toxoplasma gondii, a unique conoid-localized β-strand-swapped homodimer, is required for an efficient parasite growth. FASEB J. 2013 Mar;27(3):1034-47. doi: 10.1096/fj.11-180992. Epub 2012 Dec 11. PMID: 23233536.

*equally contributed

** Corresponding Author 

Course Catalogue